Curriculum Vitae

Education

2018 PhD in Neuroscience, Johns Hopkins University School of Medicine

2012 Honours BSc, University of Toronto

Research Experience

2019- Postdoctoral Scholar, University of California San Francisco

2013-2019 Predoctoral IRTA Fellow, National Institute on Drug Abuse

2010-2012 Research Assistant, University of Toronto

Other Professional Training

2019 Journal of Neuroscience Reviewer Mentoring Program

2019 UCSF TRAIN-UP Inclusive Research Mentor Course

2015 Cellular Biology of Addiction Course (TA), Cold Spring Harbor Laboratory

2013 Summer Course - 'Neural Circuits from Top to Bottom', RIKEN Brain Science Institute

Fellowships and Funding

2020-2022 NINDS Ruth L. Kirschstein National Research Service Award (F32), National Institutes of Health

2016-2019 Predoctoral IRTA Fellowship, National Institutes of Health

2013-2016 Graduate Research Fellowship, National Science Foundation

Awards and Honors

2022 Honoree - Rising Stars in MS Research, National Multiple Sclerosis Society Northern California Chapter

2021 Network Glia Travel Award, XV European Meeting on Glial Cells in Health and Disease

2019 Chair-Elect, 2021 Gordon Research Seminar on Glial Biology

2019 Outstanding Poster Award, Winter Conference on Brain Research

2018 Student Poster Award, Annual Greater Baltimore Chapter SfN Chapter Meeting

2018 Travel Fellowship, Winter Conference on Brain Research

2018 Faculty nominated speaker, Johns Hopkins University Annual Neuroscience Retreat

2018 Outstanding Poster Award, National Institute on Drug Abuse IRP

2018 Graduate Student Research Award, National Institutes of Health

2017 Student Poster Award, Johns Hopkins University Annual Neuroscience Retreat

2017 Fellows Award for Research Excellence (FY2018), National Institutes of Health

2017 Travel Award, Johns Hopkins University Graduate Student Association

2015 Fellows Award for Research Excellence (FY2016), National Institutes of Health

2013 Thomas J. and Mary L. Kelly Award for Young Scholars, Johns Hopkins University

2012 Excellence Award in Natural Sciences and Engineering, University of Toronto

2010-2012 Dean's List, University of Toronto Faculty of Arts and Sciences

2011 Student Travel Award, Annual AIRS Meeting

2010 In-course Scholarship, New College, University of Toronto

Teaching Experience

2021-2022 Lecturer, Basic Concepts for Cellular and Developmental Neuroscience, UCSF

2013-2016 Instructor, RISE Summer Workshop on Statistics and Experimental Design, Morgan State University

2015 Teaching Assistant, Great Discoveries in Neuroscience Course, JHU

2014 Teaching Assistant, Neuropharmacology Course, JHU School of Medicine

2014 Teaching Assistant, Neurobiology of Substance Abuse, JHU School of Medicine

Academic Service and Outreach

Journal Peer Review ( * with advisor)

Journal of Neuroscience, eNeuro, Trends in Neurosciences, Brain Structure and Function, European Journal of Neuroscience, Frontiers in Cellular Neuroscience, Nature*, Nature Neuroscience*, Cell*, Cell Reports*, Neuron*, Immunity*, Journal of Experimental Medicine*, Brain*, Glia*

Leadership and Outreach

2022 Panelist, Society for Neuroscience Webinar - 'Navigating the postdoc-PI relationship'

2022 Panelist, Johns Hopkins Neuroscience Careers Course - 'Finding a postdoc and the postdoc experience'

2021- Mentor, Project SHORT - https://www.project-short.com/

2021 Guest Editor, Frontiers in Behavioral Neuroscience Research Topic - 'The Role of Stress in Addictive Behaviors'

2021 Interviewee, 'A conversation on the effects of the COVID-19 pandemic on academic careers with junior researchers' - https://www.nature.com/articles/s41467-021-22039-w

2020-2021 Founder and co-chair, Virtual Glia Trainee Symposium - http://www.virtualglia.org/

2020 Interviewee, Once A Scientist Podcast - https://onceascientist.net/2020/04/21/ep9/

2019-2020 Co-organizer, Postdoc meeting with speakers, UCSF Neuroscience Formal Seminar Series

2018 Volunteer, Baltimore BrainFest - https://www.brainfest.org

2013-2017 Recruitment Committee, Johns Hopkins SoM Neuroscience Graduate Program

2016 Instructor, NSF GRFP workshop, JHU SoM Department of Neuroscience

2014-2016 3rd and 4th year representative, JHU SoM Neuroscience Graduate Program

2013-2016 Co-founder and committee chair, Project Bridge - http://www.projbridge.org

2013-2014 Organizing Committee, JHU SoM Annual Neuroscience Retreat

2012-2013 Steering Committee, Career Development Course, JHU SoM Graduate Student Association

Publications ( # corresponding, * equal contribution)

2022 Xin W#, Chan JR#. Motor learning revamps the myelin landscape. Nature Neuroscience, 25: 1251-1252.

2022 Cordano C, Sin JH, Timmons G, Yiu HH, Stebbins K, Guglielmetti C, Cruz-Herranz A, Xin W, Lorrain D, Chan JR, Green AJ. Validating visual evoked potentials as a preclinical, quantitative biomarker for remyelination efficacy. Brain, awac207.

2021 Sell GL*, Xin W*, Cook EK*, Zbinden MA, Schaffer TB, O’Meally RN, Cole RN, Margolis SS. Deleting a UBE3A substrate rescues impaired hippocampal physiology and learning in Angelman syndrome mice. Scientific Reports, 11: 19414.

2021 Chen JF, Liu K, Hu B, Li RR, Xin W, Chen H, Wang F, Chen L, Li RX, Ren SY, Xiao L, Chan JR, Mei F. Enhancing myelin renewal reverses cognitive dysfunction in a murine model of Alzheimer’s disease. Neuron, 109: 1-16.

2021 Chang KJ, Agrawal I, Vainshtein A, Ho WY, Xin W, Tucker-Kellogg G, Susuki K, Peles E, Ling SC, Chan JR. TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells. eLife, 2021; 10:e64456.

2020 Xin W#, Chan JR#. Myelin plasticity: sculpting circuits in learning and memory. Nature Reviews Neuroscience, 21: 682–694.

2020 Marino RAM, McDevitt RA, Gantz S, Pignatelli M, Xin W, Wise RA, Bonci A. Control of food approach and eating by a GABAergic projection from lateral hypothalamus to dorsal pons. Proceedings of the National Academy of Sciences, 117(15): 8611-8615.

2020 Xin W#, Chan JR. That wasn’t a Complement – too much C3 in demyelinating disease. Immunity, 52(1): 11-13.

2019 Xin W#, Mironova YA, Shen H, Marino RAM, Waisman A, Lamers WH, Bergles DE, Bonci A#. Oligodendrocytes support neuronal glutamatergic transmission via expression of glutamine synthetase. Cell Reports, 27(8): 2262-2271.

2018 Xin W#, Schuebel K, Jair K-W, Cimbro R, Debiase LM, Goldman D, Bonci A#. Ventral midbrain astrocytes display unique physiological features and sensitivity to dopamine D2 receptor signaling. Neuropsychopharmacology, 44(2): 344-355.

2018 Xin W# & Bonci A#. Functional astrocyte heterogeneity and implications for their role in shaping neurotransmission. Frontiers in Cellular Neuroscience, 12:141.

2016 Xin W*, Edwards N*, & Bonci A. VTA Dopamine Neuron Plasticity - The Unusual Suspects. European Journal of Neuroscience, 44(12): 2975-2983.

Preprints

2019 Faust TE, Xin W, Lee B, Agarwal A, Saha S, Palen T, Cash-Padgett T, Wood D, Bonci A, Fahey JW, Jaaro-Peled H, Bergles DE, Sawa A. Astrocyte redox dysregulation causes prefrontal hypoactivity: sulforaphane treats non-ictal pathophysiology in ALDH7A1-mediated epilepsy. bioRxiv.

2019 Sell GL*, Xin W*, Cook EK*, Zbinden MA, Schaffer T, O’Meally RN, Cole RN, Bonci A, Margolis SS. Deleting a UBE3A substrate rescues impaired hippocampal function and learning in Angelman syndrome mice. bioRxiv.

Selected Talks ( * invited)

2022 Annual Meeting of the American College of Neuropsychopharmacology, Phoenix, USA

2020 Children's Hospital of Philadelphia / University of Pennsylvania (virtual)*

2019 Nankai University Centennial Celebration Forum, Tianjin, China*

2019 Winter Conference on Brain Research, Snowmass, USA

2018 Annual Greater Baltimore SfN Chapter Meeting, Baltimore, USA

2018 Baltimore Brain Series, University of Maryland, Baltimore, USA

2018 Annual Neuroscience Retreat, Johns Hopkins University, Cambridge, USA*

2018 CSHL Meeting: Glia in Health and Disease, Cold Spring Harbor, USA

Selected Poster Presentations

2021 Glial Biology in Medicine Conference (virtual)

2021 XV European Meeting on Glial Cells in Health and Disease (virtual)

2019 XIV European Meeting on Glial Cells in Health and Disease, Porto, Portugal

2019 Gordon Research Conference on Glial Biology, Ventura,USA

2018 Annual meeting of the Society for Neuroscience, San Diego, USA

2017 Gordon Research Conference on Glial Biology, Ventura, USA

2016 Annual meeting of the Society for Neuroscience, San Diego, USA

2016 CSHL Meeting: Glia in Health and Disease, Cold Spring Harbor, USA

2015 XII European Meeting on Glial Cells in Health and Disease, Bilbao, Spain