Selected

All Publications

PRIMARY RESEARCH

2026 | Astrocyte redox imbalance underlies prelimbic neuronal 1 hypoactivity and maladaptive affective behaviors in epilepsy. Faust TE, Saito A, Ishikawa S, Yang K, Xin W, Namkung H, Agarwal A, Ramos A, Lee BJ, Hayes L, Srivastava R, Adelakun S, Saha S, Palen T, Cash-Padgett T, Wood DJ, Carloni E, Yusa R, Jaaro-Peled H, Fahey JW, Bergles DE, Ishizuka K, Sawa A†.

Science Advances, 12, eaef6777. doi.org/ 10.1126/sciadv.aef6777

Preprint - doi.org/10.1101/796474

2025 | Markers of axonal injury in blood and tissue triggered by acute and chronic demyelination. Abdelhak A†, Cordano C, Duncan GJ, Emberley K, Nocera S, Xin W, Ananth K, Jabassini N, Ning K, Reinsberg H, Cosima Oertel F, Beaudry-Richard A, Kuhle J, Petzold A, Patel PJ, Ribeiro Reis AP, Foster P, UKBB Eye and Vision Consortium, Watkins T, Chan JR, Emery B, Green AJ†.

Brain, 148 (8). doi.org/10.1093/brain/awaf144

2024 | Oligodendrocytes and myelin limit neuronal plasticity in visual cortex. Xin W†, Kaneko M, Roth RH, Zhang A, Nocera S, Ding JB, Stryker MP, Chan JR†.

Nature, 633. doi.org/10.1038/s41586-024-07853-8

Preprint - doi.org/10.1101/2023.09.29.560231

2022 | Validating visually evoked potentials as a pre-clinical, quantitative biomarker for remyelination efficacy. Cordano C, Sin JH, Timmons G, Yiu HH, Stebbins K, Guglielmetti C, Cruz-Herranz A, Xin W, Lorrain D, Chan JR†, Green AJ†.

Brain, 145 (11). doi.org/10.1093/brain/awac207

2021 | Enhancing myelin renewal reverses cognitive dysfunction in a murine model of Alzheimer’s disease. Chen JF, Liu K, Hu B, Li RR, Xin W, Chen H, Wang F, Chen L, Li RX, Ren SY, Xiao L†, Chan JR†, Mei F†. 

Neuron, 109. doi.org/10.1016/j.neuron.2021.05.012

2021 | Deleting a UBE3A substrate rescues impaired hippocampal physiology and learning in Angelman syndrome mice. Sell GL*, Xin W*, Cook EK*, Zbinden MA, Schaffer TB, O’Meally RN, Cole RN, Margolis SS†.

Scientific Reports, 11: 19414. doi.org/10.1038/s41598-021-97898-w

Preprint - doi.org/10.1101/625418

2021 | TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells. Chang KJ, Agrawal I, Vainshtein A, Ho WY, Xin W, Tucker-Kellogg G, Susuki K, Peles E, Ling SC†, Chan JR†.

eLife, 10: e64456. doi.org/10.7554/eLife.64456

2020 | Control of food approach and eating by a GABAergic projection from lateral hypothalamus to dorsal pons. Marino RAM, McDevitt RA, Gantz S, Pignatelli M, Xin W, Wise RA, Bonci A†.

Proceedings of the National Academy of Sciences, 117 (15). doi.org/10.1073/pnas.1909340117

2019 | Oligodendrocytes support neuronal glutamatergic transmission via expression of glutamine synthetase. Xin W†, Mironova YA, Shen H, Marino RAM, Waisman A, Lamers WH, Bergles DE, Bonci A†. 

Cell Reports, 27 (8). doi.org/10.1016/j.celrep.2019.04.094  

2018 | Ventral midbrain astrocytes display unique physiological features and sensitivity to dopamine D2 receptor signaling. Xin W†, Schuebel K, Jair K-W, Cimbro R, Debiase LM, Goldman D, Bonci A†. 

Neuropsychopharmacology, 44 (2). doi.org/10.1038/s41386-018-0151-4

REVIEWS AND COMMENTARIES

2026 | Glia orchestrate neural circuit development. Sakers K*, Sheehan P*, Xin W*†, Schafer D†, Eroglu C†.

Developmental Cell, 61 (7): 1407-1430. doi.org/10.1016/j.devcel.2026.06.008

2024 | Glial control of cortical neuronal circuit maturation and plasticity. Faust TE†, Devlin B, Farhy-Tselnicker I, Ferro A, Postolache M, Xin W†.

Journal of Neuroscience, 44 (40). doi.org/10.1523/jneurosci.1208-24.2024

2022 | Motor learning revamps the myelin landscape. Xin W†, Chan JR†.

Nature Neuroscience, 25. doi.org/10.1038/s41593-022-01156-9

2020 | Myelin plasticity: sculpting circuits in learning and memory. Xin W†, Chan JR†.

Nature Reviews Neuroscience, 21. doi.org/10.1038/s41583-020-00379-8

2020 | That wasn’t a Complement – too much C3 in demyelinating disease. Xin W†, Chan JR.

Immunity, 52 (1). doi.org/10.1016/j.immuni.2019.12.014

2018 | Functional astrocyte heterogeneity and implications for their role in shaping neurotransmission. Xin W† & Bonci A†.

Frontiers in Cellular Neuroscience, 12: 141. doi.org/10.3389/fncel.2018.00141

2016 | VTA Dopamine Neuron Plasticity – The Unusual Suspects. Xin W*, Edwards N*, & Bonci A†.

European Journal of Neuroscience, 44 (12). doi.org/10.1111/ejn.13425

†corresponding *equal contribution